- info@seqmatic.com
Mon - Fri 9AM - 7PM PST
Mon - Fri 9AM - 7PM PSTA Broad Range of Multiomics
SeqMatic provides end to end CRO laboratory services with flexible entry points across the full NGS and omics workflows, from nucleic acid extraction and library preparation through sequencing and bioinformatics analysis. In addition to core DNA and RNA sequencing, SeqMatic offers single cell RNA sequencing on certified 10x Genomics and Parse Biosciences platforms, epigenome profiling (ATAC seq, methyl seq, ChIP seq), spatial transcriptomics (Visium, CytAssist), and histopathology services including tissue processing, staining, whole slide imaging and Pathologist review.
All services are performed at SeqMatic’s CLIA/CAP accredited laboratory in Fremont, California. SeqMatic does not subcontract work to third party or overseas facilities. For sequencing, the laboratory operates Illumina, Ultima Genomics, PacBio and Oxford Nanopore sequencing platforms, with most sequencing projects completed in 1 to 2 weeks and express turnaround available.
Every project begins with a scientific consultation. SeqMatic’s team helps you select the right platform, chemistry, and sequencing depth for your experimental design, with particular expertise in challenging sample types including low input, degraded, and FFPE material.
SeqMatic supports the full range of next generation sequencing and Multi Omics applications, from partial to complete project workflows. Each service below links to a dedicated page with detailed specifications, sample requirements, and turnaround times.
Use DNA sequencing to detect genetic variants, assemble genomes, and discover biomarkers, supporting applications from population genomics to clinical research and precision medicine.
Use RNA sequencing to measure gene expression, discover novel transcripts, and profile regulatory RNAs, from biomarker discovery to studies of disease mechanisms.
Use single cell RNA sequencing to resolve cell type heterogeneity, map developmental trajectories, and profile immune responses at single cell resolution.
Use epigenomics to map chromatin accessibility, DNA methylation, and protein DNA interactions, revealing how gene regulation drives development and disease.
Use spatial transcriptomics to map gene expression within intact tissue, linking molecular profiles to histology for cancer, neuroscience, and developmental research.
Use histopathology to evaluate tissue morphology through sectioning, staining, and pathologist review, as a standalone service or paired with spatial transcriptomics.
Use bioinformatics to turn raw sequencing data into biological insight through custom pipelines, including support for non-model organisms and de novo assembly.
SeqMatic accepts a wide range of sample types across all service categories. For DNA and RNA sequencing, the laboratory accepts extracted nucleic acids, tissue (animal and plant), cells, whole blood, plasma, serum, soil, fecal specimens, environmental samples, FFPE blocks and sections, and cryopreserved material. For single cell RNA sequencing, the laboratory accepts single cell suspensions,
intact tissues for dissociation, isolated nuclei, and fixed or frozen cells. SeqMatic specializes in the handling of low input, challenging, and degraded samples, and accepts samples at any stage of the sequencing workflow, from raw tissue through pre-made libraries ready for sequencing.
SeqMatic operates multiple sequencing platforms to match different throughput, read length, and cost requirements:
SeqMatic is a Certified Service Provider for Illumina.
For sequencing, most standard sequencing projects are completed within 1 to 2 weeks from sample receipt to data delivery. Express turnaround is available in as few as 3 to 5 days for sequencing services.
For workflows, projects follow separate turnaround timelines; see the relevant service pages for project specific estimates. Actual turnaround depends on sample complexity, the number of samples, sequencing depth, and bioinformatics scope.
Yes. SeqMatic has a full time in-house bioinformatics team that supports all service types, with a full suite of custom analytic pipelines that can be tailored to individual project needs, including support for non-model organisms. Available analyses include:
This list is not all inclusive. If your analyses of interest is not listed, contact SeqMatic to discuss feasibility.
Yes. If you prepare your own sequencing libraries, SeqMatic can perform QC, sequencing, and data analysis on pre-made libraries. This option is available across all sequencing platforms. SeqMatic validates every in-house prepared library via MiSeq QC sequencing before committing to the production run, and the same QC step is available for customer-prepared libraries.
Yes. SeqMatic provides histopathology services including necropsy and grossing, tissue processing, embedding and sectioning, histological staining assays ( routine stains (H&E), special stains (i.e.Trichrome, VVG, PAS), and advanced stains (IHC, IF)), and automated whole slide imaging, image analysis, as well as Pathologist review (California Board Certified Pathologist). These services can be performed as standalone assays or integrated with spatial transcriptomics (Visium, CytAssist) for combined morphological and gene expression profiling from the same tissue section.
