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Many providers focus exclusively on research or clinical testing. SeqMatic bridges both worlds. Our integrated capabilities support discovery research, biomarker identification, translational studies, assay development, clinical validation, and regulated laboratory workflows. Customers can advance programs from concept to clinical application without changing laboratory partners.
Every project is performed within our Fremont, California facility. We do not outsource laboratory operations to overseas facilities or third party providers. Maintaining complete operational control lets us deliver greater sample security, stronger chain of custody oversight, faster communication, consistent quality standards, reduced project risk, and BIOSECURE Act aligned operations.
Our laboratory is CLIA certified, CAP accredited, California state licensed, and GLP compliant, operating under rigorous quality management systems designed to support both research and regulated applications. Customers gain confidence that their data can withstand scientific, regulatory, and clinical scrutiny.
SeqMatic combines the accessibility and scientific engagement of a specialized research partner with the infrastructure, quality systems, and scalability required to support large and complex programs. Whether you are launching a pilot study, supporting a global clinical trial, or generating data for regulatory submissions, our team scales with your needs while maintaining the personalized support customers often lose with larger providers.
Customers work directly with the bench scientists responsible for their projects. Our team provides guidance on experimental design, workflow selection, sample quality, data interpretation, and troubleshooting throughout the project lifecycle. This collaborative approach helps maximize data quality while reducing costly delays and repeat experiments.
The best technology depends on the scientific question. SeqMatic supports leading genomics platforms including Illumina, PacBio, Oxford Nanopore, Ultima Genomics, 10x Genomics, and Parse Biosciences. Because we are not limited to a single technology ecosystem, we can recommend the approach that best serves your scientific objectives.
Not every project requires a full workflow, and not every sample travels well. SeqMatic supports any or all segments of the omics workflow, so customers can enter at extraction, at purified DNA or RNA, or with prepared libraries, and add primary, secondary, or tertiary bioinformatics as needed. For San Francisco Bay Area customers, Fetch-Seq courier pickup and Onsite-Seq in lab cell fixation protect sample quality and chain of custody where viability is time sensitive. And because histopathology runs in house, tissue projects move from grossing and sectioning through staining, pathologist review, and spatial workflows without leaving the building or the chain of custody.
More than 700 organizations worldwide have trusted SeqMatic to support projects in oncology, immunology, neuroscience, drug development, agricultural genomics, environmental biology, and human genetics. Data generated by SeqMatic has contributed to more than 450 peer reviewed publications and has supported discoveries that advance both science and medicine.
Our customers choose SeqMatic because they need more than sequencing capacity. They need a scientific partner committed to helping them generate reliable results, accelerate timelines, and move confidently from discovery to decision.
SeqMatic’s scientific work is led by a team with distinct areas of responsibility. Su Chen, MD, PhD, Medical Director, provides clinical oversight, interpretation, and clinical reporting, along with pathology reviews and histology expertise. Kelvin Chan, VP of Technology, focuses on operations, development, troubleshooting, customer consultations, new technologies, and bioinformatics. Ann Frazier, Associate Director of Clinical Laboratory, leads day to day laboratory operations and clinical workflows. Customers work directly with the scientists responsible for their projects, which is central to how SeqMatic maintains data quality. Kelvin also serves as the designated technical reviewer for SeqMatic’s published scientific content.
SeqMatic operates under documented quality management systems consistent with CLIA and CAP requirements. Every sample undergoes QC checks on receipt before library preparation and/or sequencing begins. Every library prepared in house is validated by MiSeq QC sequencing before committing to the production run, so library quality issues are caught before they consume reagent and instrument time. Sequencing performance is monitored against vendor yield specifications, which SeqMatic has historically outperformed across run types. SeqMatic does not mix samples from multiple customer projects in a single run, avoiding the risk of cross contamination and index (barcode) hopping. Bioinformatics outputs follow platform standard pipelines, with custom reference construction available for non-model organisms.
SeqMatic works with biotech and pharmaceutical companies, clinical laboratories, academic researchers and core facilities, agricultural and environmental research groups, government agencies, and other contract research organizations. Project scale spans single sample pilots through atlas scale studies. The lab handles traditional human and mouse (model) organisms and specializes in non-model organisms such as non-human primate, livestock, plant, marine, wildlife, domestic animals, and other unique species. CLIA/CAP accreditation means projects can begin under research use only and transition to clinical or regulated workflows in the same facility without changing service providers.
Yes. SeqMatic supports any or all segments of the omics workflow that best fits customer needs. For example, you can send blood, cells, or tissues that require extraction, purified DNA/RNA, or prepared libraries, and we will complete the workflow through sequencing. We also offer primary, secondary, and tertiary bioinformatics as needed.
SeqMatic is located in Fremont, California, and all work is performed in our Fremont laboratory. We do not outsource to third parties or send your samples overseas. For San Francisco Bay Area customers, SeqMatic offers a door to door courier pickup service called Fetch-Seq. A courier collects your samples as soon as they are ready and delivers them directly to the SeqMatic lab, typically within about an hour of pickup, so chain of custody can be tracked in real time from pickup to delivery. For customers running single cell workflows, where project success depends heavily on cell viability, SeqMatic offers Onsite-Seq: our scientists travel to your lab with all the equipment needed and can fix cells or perform GEM creation on site. Once the cells are stable, we hand carry them back to the SeqMatic lab to complete the single cell workflow.
Yes. SeqMatic operates a full service histopathology lab that accepts tissues either cryopreserved (snap frozen) for frozen processing or in formalin for FFPE processing. We can gross and trim tissues, process, embed, section, stain, digitally scan, and analyze tissues, including pathologist review. We offer a wide range of tissue staining including routine, special, immunohistochemistry (IHC), and histochemical stains. Histology for spatial transcriptomics is a particular strength, including custom tissue microarrays (TMAs) designed to allow more tissues per spatial slide, reducing the cost of spatial analysis per tissue.
The BIOSECURE Act, enacted in December 2025 as part of the Fiscal Year 2026 National Defense Authorization Act, restricts US federal agencies, contractors, and grant recipients from using biotechnology equipment or services from designated biotechnology companies of concern, defined as entities owned or controlled by foreign adversary governments. SeqMatic is a US owned and operated, CLIA certified laboratory in Fremont, California. All work is performed in house in the United States, with no subcontracting to third party or overseas facilities. SeqMatic’s US based operations align with the supply chain objectives the Act addresses. SeqMatic is also SOC 2 and HIPAA compliant.
For over a decade, we’ve been earning trust and respect as a reliable outsourcing partner for research and clinical sequencing. Experienced NGS CRO lab services like ours are uniquely positioned to fulfill your NGS and multi-omics’ needs.
The SeqMatic approach starts with proven genomic workflows and proprietary controls that have been refined and optimized over the past decade.
The SeqMatic approach starts with proven genomic workflows and proprietary controls that have been refined and optimized over the past decade.
View More We learn about the goals of our customer’s scientific research and the type of omics and sequencing data that would be most beneficial to their project.
We learn about the goals of our customer’s scientific research and the type of omics and sequencing data that would be most beneficial to their project.
View More Then we modify our workflows to target those specific goals and reads. Couple that effort with world class turnaround time.
Then we modify our workflows to target those specific goals and reads. Couple that effort with world class turnaround time.
View More The application of best science, higher quality data, more read depth per lane, and fast delivery makes SeqMatic an exceptional partner and value per research dollar spent.
The application of best science, higher quality data, more read depth per lane, and fast delivery makes SeqMatic an exceptional partner and value per research dollar spent.
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