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RNA Sequencing (RNA-seq) Services

QUANTIFYING GENE EXPRESSION & GENE REGULATION

RNA sequencing (RNA-seq) services provide comprehensive gene expression profiling. The profiling quantification and transcription activation is enabled by RNA sequencing methods (RNA-Seq) on a genome-wide scale. At SeqMatic, RNA sequencing services are carried-out daily for a variety of organisms and a wide-range of applications related to genomics, transcriptomics, epigenomics and a multitude of other omics.

Popular RNA sequencing (RNA-Seq) services applications completed by SeqMatic include:

RNA Service Features

Expert pooling validated by MiSeq Nano – to ensure equal sample distribution

Proprietary TailorMix PhiX control – For reducing cross-talk during data processing and analysis

Scalability from pilot to production – One partner for any scale project – equipped to support any size project – no sample minimum or maximum!

A wide-range of RNA kits – tailored to sample type which deplete unwanted background RNA from the target of interest.  The increased sensitivity means more and cleaner data

All RNA projects are performed in a CLIA environment – To ensure consistent quality

RNA Service Highlights

Comprehensive Services – Complete RNA workflow, including extraction from virtually any sample type, library generation, sequencing, and data analysis services

Prepared Libraries From Difficult Samples – We have experience working with low input, cfRNA, si/miRNA, archival, non-model organisms, FFPE, etc.

Stringent Quality Controls – All sample preparation and library construction steps are validated by multiple assays (Qubit, TapeStation, qPCR and test sequencing)

Fast Turnaround Time – Standard and Express Services available

Technical Support – QC reports prepared for review by customer to decide which samples qualify for library preparation, or alternative library preparation/sample re-submission

Flexibility – From small projects with low input to large scale projects with high-throughput. Manually or automated using a wide-range of processing technologies

Wide-range of Sample Types – human, animal, fish, plant, bacteria/fungi, environmental, viruses/phages from virtually any source

If you have RNA – we can sequence it!!

Hand of research scientist working with microplate for laboratory analysis

Sequencing RNA is widely used in cancer research, including for biomarker identification and characterization of cancer heterogeneity, drug resistance, immune microenvironment and immunotherapy, neoantigen discovery, and other aspects and applications.

RNA plays a crucial role in gene expression as it serves as a mediator between the genetic information stored in DNA and proteins. RNA sequencing leverages high-throughput sequencing techniques to gain insights into a cell’s transcriptome; and enables researchers and scientists to:

      • learn more details about human genetic variation
      • screen new treatments and therapies
      • prepare for genetic research projects
      • identify the genetic causes of diseases
      • study human evolution

The SeqMatic Difference

Expert NGS

The SeqMatic approach starts with proven genomic workflows and proprietary controls that have been refined and optimized over the past decade to deliver considerably more data than Illumina specifications.

Expert NGS

The SeqMatic approach starts with proven genomic workflows and proprietary controls that have been refined and optimized over the past decade to deliver considerably more data than Illumina specifications.

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Conscientious Attention To Detail

We learn about the goals of our customer’s scientific research and the type of sequencing data that would be most beneficial to their project.

Conscientious Attention To Detail

We learn about the goals of our customer’s scientific research and the type of sequencing data that would be most beneficial to their project.

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Tailor-made Services with Fast TAT

Then we modify our workflow to target those specific reads. Couple that effort with world class turnaround time.

Tailor-made Services with Fast TAT

Then we modify our workflow to target those specific reads. Couple that effort with world class turnaround time.

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Optimal Solutions to Research Needs

This application of best science, higher quality data, more read depth per lane, and fast delivery makes SeqMatic an exceptional partner and value per research dollar spent.

Optimal Solutions to Research Needs

This application of best science, higher quality data, more read depth per lane, and fast delivery makes SeqMatic an exceptional partner and value per research dollar spent.

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Get Your Results

Optimal solutions are custom-made according to research needs

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Pre-Submission

Planning & Consultation - Assurance of de-identified sample submission and handling

Sample Submission

Nucleic Acid Extraction - We accept a wide range of sample types

Library Preparation

Library Generation - Amplified cDNA is used for sequence libraries' construction

Sequencing

Different platforms for different data outputs

Data Analysis

Custom BioInformatics